Balancing Mucosal Immunity: Caught between CYLD and Charybdis
نویسندگان
چکیده
منابع مشابه
Caught between Scylla and Charybdis? Regulating Bank Leverage When There Is Rent-seeking and Risk-shifting
We consider a model in which banking is characterized by asset substitution moral hazard and managerial under-provision of effort in loan monitoring. The privately-optimal bank leverage efficiently balances the benefit of debt in providing the discipline to ensure that the bank monitors its loans against the benefit of equity in attenuating asset-substitution moral hazard. However, when correla...
متن کاملCaught between Scylla and Charybdis? Regulating Bank Leverage When There Is Rent-seeking and Risk-shifting
We consider a model in which banks face two moral hazard problems: 1) asset substitution by shareholders, which can occur when banks make socially-inefficient, risky loans; and 2) managerial under-provision of effort in loan monitoring. The privately-optimal level of bank leverage is neither too low nor too high: It efficiently balances the market discipline that owners of risky debt impose on ...
متن کاملBetween Scylla and Charybdis.
The ethical dilemmas of treating fulminant (or subfulminant) hepatic failure with liver replacement have been apparent since the earliest trials of this procedure. Acute hepatic failure was the indication for orthotopic liver transplantation in only I of our first 237 recipients I and accounted for only 8 of the next 300.2 Our reluctance to proceed with more cases was that unlike candidates who...
متن کاملMucosal immunity.
Food allergy is the manifestation of an abnormal immune response to antigen delivered by the oral route. Normal mucosal immune responses are generally associated with suppression of immunity. A normal mucosal immune response relies heavily on a number of factors: strong physical barriers, luminal digestion of potential antigens, selective antigen sampling sites, and unique T-cell subpopulations...
متن کاملMucosal Immunity and Vaccines
These mucosal surfaces, while located inside the body, are actually a physical barrier between the outside and the sterile interior cavity of the body known as the “systemic” environment. Critical nutrients, oxygen and other molecules are constantly taken up across these mucosal barriers; however, another important function of the mucous is to keep invading pathogens out [15]. Daily these mucou...
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ژورنال
عنوان ژورنال: Immunity
سال: 2007
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2007.08.004